SECTION C: (4 MARKS QUESTIONS)
The tetra-peptide “KDEL” is well-known as a retrieval signal of several newly synthesized proteins. This process is mediated through specific-KDEL interaction. Any single amino acid change in this tetrapeptide is not allowed in terms of its binding with its receptors and its subsequent retention in specific organelle whereas, secretory proteins are devoid of such tetra-peptide. From this observation indicate the localization of the receptor of this tetrapeptide:
A. Plasma membrane
B. Golgi
C. Endoplasmic reticulum
D. Mitochondria