A null mutation is created in a gene which is responsible for specific phosphorylation at 6th carbon position of mannose on acid hydrolase occuring in cis-Golgi. The following statements are given towards explaining the effect of this mutation.
a) The lysosomes will be devoid of lysosomal enzymes.
b) Lysosomal enzymes will be secreted out.
c) Lysosomal enzymes will get localized in the cytoplasm
Which statement or combination of statements will explain the effect of mutation if the acid hydrolases in the mutant do not get degraded?
A. a and c
B. b and c
C. c only
D. a and b